Conference Day One

Wednesday April 24, 2024

8:00 am Morning Registration & Coffee

9:00 am Chair’s Opening Remarks

Standardizing Practice for Clinical Use & Regulatory Progress

9:15 am Sources and Regulatory Takeaways From Products Marketed Around The Globe

  • Duncan Ross Chief Executive Officer & Founder, Kimera Labs


  • Exploring the popularity of the word exosome in regenerative medicine
  • Addressing the diversity of sources of these cellular signaling machines
  • Discussing sources as well as regulatory requirements in various markets

Advancing Isolation & Quantification of Exosomes to Ensure Accurate Analysis

9:45 am Characterization by Purification: Use of AEX, Density Gradient UC, & SEC to Analyze Charge, Density, & Size of Various Particle Subpopulations


  • Building from the definitions of various subpopulations to detect clearly whether a sample is pure for the most accurate results
  • Defining clear differentiating properties of these highlighted subpopulations for further use
  • Creating clear strategies to transfer to future studies

10:15 am Morning Refreshments & Speed Networking


As some of the Exosome community is reunited, this session provides a valuable opportunity to make meaningful and lasting connections with your peers in the room. All attendees will have the opportunity to meet their fellow academic and industry experts.

11:45 am Generation of Stably Transduced MSCs to Purification of Engineered EVs

  • Inkyu Lee Business Development Senior Manager , SHIFTBIO INC.


  • Engineering MSCs through SBI’s Platform Technology, Extracellular Vesicle Sorting Motif (ESM)
  • Exploring Upstream and Downstream Process Developments of Engineered EVs
  • Ensuring Scalability and Batch-to-Batch Consistency of Engineered EVs 

12:15 pm Lunch & Networking

1:15 pm Case Study: Repair Assays & Large Scale Preparation & Validation of Reparative EVs


  • Reviewing a recent report from George Mason University and what it has uncovered for future use
  • Building on pre-existing purification methods and what needs to be resolved
  • Discussing the standards for large scale preparation for consistent future use

1:45 pm Case Study: Utilizing EV miRNAs to Uncover Underlying Molecular Mechanisms of Asthma Phenotypes


  • Challenges in establishing a methodological workflow for EV miRNA-Sequencing analysis
  • Bronchial Epithelial Cells secret EVs differ in size and miRNA cargo in apical and basal compartments
  • EV plasma miR-17 and -106a clusters associated specifically with obesity-associated low type-2 asthma

2:15 pm Afternoon Refreshments

3:15 pm Methods of Quantification for Emerging Assays for Future Use


  • Validity of purification methods to ensure accuracy
  • Using a combination of quantification techniques to differentiate exosome subtypes in heterogenous samples
  • Ensuring more products are making it to later clinical stages of your pipeline

3:45 pm Roundtable Discussion: Future Directions & Predictions for Exosome Space with Regulatory Confidence


  • More practical and highly interactive breakout roundtables where attendees can crowdsource solutions and share opinions around pre-assigned topic areas. A valuable chance for attendees to unite around hot topics and debate best practice. This is a dedicated opportunity for you to voice your experience and identify unique solutions.

4:45 pm Chairs Closing Remarks

5:00 pm Close of Day One